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E3 Ligase Ligand-linker Conjugate 91

Product Specifications

CAS Number

2229713-40-8

Target

E3 Ligase Ligand-Linker Conjugate

Related Pathways

PROTAC

Bioactivity

E3 Ligase Ligand-linker Conjugate 91, a conjugate of an E3 ligase ligand and linker, consists of (S, R, S) -AHPC and the corresponding linker. (S, R, S) -AHPC is a VH032-based von Hippel-Lindau (VHL) ligand that recruits VHL proteins. This conjugate serves as a key intermediate for synthesizing complete PROTAC molecules.

Smiles

C([C@@H](NC(COCCN1CCN(C(OC(C)(C)C)=O)CC1)=O)[C@@](C)(C)C)(=O)N2[C@H](C(NCC3=CC=C(C=C3)C4=C(C)N=CS4)=O)C[C@@H](O)C2

Molecular Formula

C35H52N6O7S

Molecular Weight

700.89

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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