DC-SX029
Product Specifications
CAS Number
300713-88-6
Target
PI3K, IκB/IKK, NF-κB
Related Pathways
PI3K/Akt/mTOR signaling, NF-κB
Bioactivity
DC-SX029 is a potent inhibitor of SNX10 protein-protein interaction (PPI) with an estimated K D constant of approximately 0.935 μM as measured by surface plasmon resonance (SPR) . It blocks the SNX10-PIKfyve interaction, leading to decreased TBK1/c-Rel signaling activation, without affecting SNX10 protein levels. DC-SX029 shows potential for inflammatory bowel disease (IBD) research [1].
Smiles
S(NCC(CCC(O)=O)C(F)(F)F)(=O)(=O)C1=CC=C(NC(OC)=O)C=C1
Molecular Formula
C14H17F3N2O6S
Molecular Weight
398.36
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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