DC-SX029
Product Specifications
CAS Number
300713-88-6
Target
PI3K|||I?B/IKK|||NF-?B
Related Pathways
PI3K/Akt/mTOR signaling|||NF-?B
Bioactivity
DC-SX029 is a potent inhibitor of SNX10 protein-protein interaction (PPI) with an estimated K D constant of approximately 0.935 ?M as measured by surface plasmon resonance (SPR) . It blocks the SNX10-PIKfyve interaction, leading to decreased TBK1/c-Rel signaling activation, without affecting SNX10 protein levels. DC-SX029 shows potential for inflammatory bowel disease (IBD) research [1].
Smiles
S(NCC(CCC(O)=O)C(F)(F)F)(=O)(=O)C1=CC=C(NC(OC)=O)C=C1
Molecular Formula
C14H17F3N2O6S
Molecular Weight
398.36
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
MBS7140869 Inquire
Rabbit anti-Danio rerio (Zebrafish)(Brachydanio rerio) NRF1 Polyclonal Antibody
Ask
View Details 
MBS2145806-01 0.1 mL
Cy3-Linked Monoclonal Antibody to Interleukin 7 Receptor (IL7R)
Ask
View Details MBS2145806-02 0.2 mL
Cy3-Linked Monoclonal Antibody to Interleukin 7 Receptor (IL7R)
Ask
View Details