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DAPM

Product Specifications

CAS Number

208255-51-0

Target

Gamma-secretase

Related Pathways

Stem Cells, Proteases/Proteasome, Neuroscience

Purity

0.9976

Bioactivity

DAPM (gamma-Secretase Inhibitor XVI) is a Notch pathway inhibitor with anticancer activity and antiproliferative effects, inhibits cell proliferation and induces the expression of Krüppel-like Factor 4 (KLF4) and p21 in human colon cancer cells, inhibits Notch signaling, and can be used in the study of renal tubular adenomas.

Smiles

[C@@H](NC([C@@H](NC(CC1=CC(F)=CC(F)=C1)=O)C)=O)(C(OC)=O)C2=CC=CC=C2

Molecular Formula

C20H20F2N2O4

Molecular Weight

390.38

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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