CYP4A11/CYP4F2-IN-2
Product Specifications
CAS Number
2280834-99-1
Target
Cytochromes P450
Related Pathways
Metabolism
Bioactivity
CYP4A11/CYP4F2-IN-2 (compound 15) serves as an orally administered inhibitor targeting CYP4A11/4F2, exhibiting IC50 values of 120 nM and 220 nM, respectively. This compound effectively suppresses 20-HETE production within the rat kidney and shows promise in mitigating the progression of diabetic nephropathy and autosomal dominant polycystic kidney disease [1].
Smiles
O(CCCCCCCOC(C(O)=O)(C)C)C1=CC=C(N=C1)C=2C=CNN2
Molecular Formula
C19H27N3O4
Molecular Weight
361.44
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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