CTSL/CAPN1-IN-2
Product Specifications
CAS Number
2410075-64-6
Target
Cysteine Protease, SARS-CoV
Related Pathways
Microbiology/Virology, Proteases/Proteasome
Bioactivity
CTSL/CAPN1-IN-2 (Compound 14b) serves as an orally active inhibitor targeting both CTSL and CAPN1, manifesting IC50 values of 6.88 nM for CTSL and 347.6 nM for CAPN1 respectively. This compound not only displays anti-inflammatory attributes but also features favorable pharmacokinetic properties. Moreover, CTSL/CAPN1-IN-2 shows extensive antiviral effects against coronaviruses by inhibiting viral entry [1].
Smiles
C(N[C@@H](CC1CCCCC1)C(N[C@@H](C[C@H]2C(=O)NCCC2)C(C(NCC3=CC=CC=C3)=O)=O)=O)(=O)C4=CC=5C(O4)=CC=CC5
Molecular Formula
C34H40N4O6
Molecular Weight
600.7
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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