Dencatistat
Product Specifications
CAS Number
2377000-84-3
Target
DNA/RNA Synthesis
Related Pathways
DNA Damage/DNA Repair, Cell Cycle/Checkpoint
Purity
0.9885
Bioactivity
Dencatistat is a highly selective and orally available cytidine triphosphate synthase 1 (CTPS1) inhibitor that specifically inhibits CTPS1 without affecting CTPS2.CTPS1-IN-2 reduces cancer cell proliferation for the treatment of B-cell, T-cell lymphomas and solid tumors.
Smiles
O=C(NC1=NC=C(C=C1)C=2N=C(OCC)C=NC2)C3(C4=NC(=NC=C4)NS(=O)(=O)C5CC5)CCOCC3
Molecular Formula
C24H27N7O5S
Molecular Weight
525.58
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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