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CSF1R-IN-15

Product Specifications

CAS Number

2925744-43-8

Target

C-Fms

Related Pathways

Tyrosine Kinase/Adaptors

Bioactivity

CSF1R-IN-15 (compound 23) serves as an inhibitor of the colony-stimulating factor-1 receptor (CSF1R), a tyrosine kinase located in the macrophage cell membrane. This receptor is activated by colony-stimulating factor-1 (CSF-1) and interleukin-34. Signaling through CSF1R is essential for the differentiation, proliferation, and survival of macrophages [1].

Smiles

N(CC1=CC(C)=CC=C1)(C)C2=C3C(NC(=C3)C4=CC=C(CO)C=C4)=NC=N2

Molecular Formula

C22H22N4O

Molecular Weight

358.44

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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