CRT0066101
Product Specifications
CAS Number
956123-34-5
Target
Apoptosis, Pim, Serine/threonin kinase
Related Pathways
Apoptosis, Chromatin/Epigenetic, Cell Cycle/Checkpoint, JAK/STAT signaling, Metabolism
Bioactivity
CRT0066101 is a potent, orally active PKD inhibitor with IC 50 values of 1 nM, 2.5 nM, and 2 nM for PKD1, PKD2, and PKD3, respectively [1]. Additionally, it inhibits PIM2 with an IC 50 of approximately 135.7 nM and demonstrates anticancer effects [2].
Smiles
OC=1C(=CC(=CC1)C2=CN(C)N=C2)C=3N=C(NC[C@@H](CC)N)C=CN3
Molecular Formula
C18H22N6O
Molecular Weight
338.41
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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