COX-2/15-LOX-IN-5
Product Specifications
CAS Number
443790-30-5
Target
Lipoxygenase|||COX|||NF-?B
Related Pathways
NF-?B|||Immunology/Inflammation|||Metabolism|||Neuroscience
Bioactivity
COX-2/15-LOX-IN-5 (Compound 4f) functions as a dual inhibitor of COX-2 and 15-LOX, demonstrating both anti-inflammatory and antioxidant properties [1]. This compound effectively reduces NF-?B activation in RAW 264.7 macrophages that is induced by lipopolysaccharide.
Smiles
S(CC(NC1=CC=C(OC)C=C1)=O)C=2N(C(=O)C(=CC3=CC=CC=C3)N2)C4=CC=CC=C4
Molecular Formula
C25H21N3O3S
Molecular Weight
443.52
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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