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COX-1-IN-1

Product Specifications

CAS Number

1369503-03-6

Target

COX

Related Pathways

Neuroscience, Immunology/Inflammation

Bioactivity

COX-1-IN-1 (compound 15a) selectively inhibits cyclooxygenase (COX), exhibiting an IC50 of 0.23 μM for COX-1 and greater than 50 μM for COX-2, resulting in a selectivity index (COX-2 IC50/COX-1 IC50) of 217. Additionally, COX-1-IN-1 effectively inhibits platelet aggregation [1].

Smiles

CC1=C(C(=NO1)C2=CC=C(OCC)C=C2)C3=CC=C(OCC)C=C3

Molecular Formula

C20H21NO3

Molecular Weight

323.39

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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