CNB-001
Product Specifications
CAS Number
1019110-87-2
Target
Lipoxygenase
Related Pathways
Metabolism
Bioactivity
CNB-001 is a potent inhibitor of 5-lipoxygenase (5-LOX) that reduces 5-LOX expression while enhancing proteasome activity. It also increases phosphorylation of eIF2α and levels of HSP90 and ATF4 in Alzheimer's disease transgenic mice, thereby limiting soluble Aβ and ubiquitinated aggregated protein accumulation. Additionally, CNB-001 maintains synapse-associated protein expression and improves memory, making it a valuable compound for Alzheimer's disease research [1].
Smiles
C(=C/C1=CC(OC)=C(O)C=C1)\C=2N(N=C(/C=C/C3=CC(OC)=C(O)C=C3)C2)C4=CC=CC=C4
Molecular Formula
C27H24N2O4
Molecular Weight
440.49
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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