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CEP-28122 mesylate hydrochloride

Product Specifications

CAS Number

1354545-57-5

Target

ALK

Related Pathways

Tyrosine Kinase/Adaptors, Angiogenesis

Bioactivity

CEP-28122 mesylate hydrochloride, a diaminopyrimidine derivative, is a potent, selective, and orally bioavailable ALK inhibitor with an IC50 of 1.9 nM, exhibiting antitumor and good pharmacokinetic activity [1].

Smiles

S(C)(=O)(=O)O.N([C@@H]1[C@@]2(C[C@]([C@@H]1C(N)=O)(C=C2)[H])[H])C3=NC(NC=4C(OC)=C5C(=CC4)CC[C@@H](CC5)N6CCOCC6)=NC=C3Cl.Cl

Molecular Formula

C29H40Cl2N6O6S

Molecular Weight

671.64

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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