CDK8-IN-14
Product Specifications
CAS Number
2924193-12-2
Target
CDK
Related Pathways
Cell Cycle/Checkpoint
Bioactivity
CDK8-IN-14 (compound 12) effectively inhibits CDK8, demonstrating an IC50 of 39.2 nM, and exhibits potent anti-AML cell proliferation effects, with a GC50 value of 0.02±0.01?M in MOLM-13 cells and 0.03±0.01?M in MV4-11 cells [1].
Smiles
C(N)(=O)C=1C=C(C=2C=C3C(=CNC3=NC2)C=4C=COC4)C=CC1
Molecular Formula
C18H13N3O2
Molecular Weight
303.31
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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