CDK2-IN-23
Product Specifications
CAS Number
2488073-20-5
Target
CDK
Related Pathways
Cell Cycle/Checkpoint
Bioactivity
CDK2-IN-23 (Compound 17), a selective and highly potent inhibitor of CDK2 (IC 50 = 0.29 nM), demonstrates pharmacodynamic inhibition of CDK2 in CCNE1-amplified mouse models. This compound is utilized in cancer research [1].
Smiles
C(F)(F)(F)C=1C(=NC(NC2CCN(S(=O)(=O)C3CC3)CC2)=NC1)C4=CN(CC(C)(C)O)N=C4
Molecular Formula
C20H27F3N6O3S
Molecular Weight
488.53
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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