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CDDD11-8

Product Specifications

CAS Number

2241659-94-7

Target

FLT|||CDK

Related Pathways

Tyrosine Kinase/Adaptors|||Cell Cycle/Checkpoint|||Angiogenesis

Bioactivity

CDDD11-8 is an orally administered, highly potent and selective CDK9 and FLT3-ITD inhibitor, with K i values of 8 nM and 13 nM, respectively. It effectively reduces the proliferation of leukemia cell lines, showing particular efficacy against those with the FLT3-ITD mutation [1] [2].

Smiles

CC=1C(C=2N3C(=NC2)C=CC(=C3)C4=CC=CC=C4)=NC(N[C@@H]5CC[C@@H](N)CC5)=NC1

Molecular Formula

C24H26N6

Molecular Weight

398.5

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Product Datasheet

https://www.targetmol.com/attachment/DataSheet/212215650406367340/T86025

Available Sizes

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