CD 10899
Product Specifications
CAS Number
1331770-20-7
Target
PLK
Related Pathways
Cell Cycle/Checkpoint
Bioactivity
CD 10899, a hydroxylated metabolite of Volasertib, is pharmacologically active against Polo-like kinase 1 (PLK1) with an IC50 of 6 nM. Volasertib is an orally active, highly potent, and ATP-competitive PLK1 inhibitor. CD 10899 can be used for cancer research [1].
Smiles
C(C)(C)N1C=2C(N(C)C(=O)C1(CC)O)=CN=C(NC3=C(OC)C=C(C(N[C@H]4CC[C@@H](CC4)N5CCN(CC6CC6)CC5)=O)C=C3)N2
Molecular Formula
C34H50N8O4
Molecular Weight
634.81
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
MBS6174720-01 0.1 mL
MAST4 (Microtubule Associated Serine/Threonine Kinase Family Member 4, DKFZp686E18148, DKFZp686N1467, FLJ16540, FLJ33039, KIAA0303) (Biotin)
Sign In for Pricing
View Details MBS6174720-02 5x 0.1 mL
MAST4 (Microtubule Associated Serine/Threonine Kinase Family Member 4, DKFZp686E18148, DKFZp686N1467, FLJ16540, FLJ33039, KIAA0303) (Biotin)
Sign In for Pricing
View Details 
MBS2002491-01 0.1 mL
Polyclonal Antibody to Angiotensin I Converting Enzyme (ACE)
Sign In for Pricing
View Details