BTL-MK
Product Specifications
CAS Number
2758569-43-4
Target
Others
Related Pathways
Others
Bioactivity
BTL-MK (Compound 19) is an orally active antiallergic agent that inhibits degranulation of mast cells with an IC50 of 6.7 μM by binding to the inhibitory receptor FcγRIIB. BTL-MK improves metabolic stability in human liver microsomes and ameliorates the allergic response in an Ovalbumin-induced food allergy mice model. It exhibits good pharmacokinetic characteristics with metabolic stability [1].
Smiles
C([C@]1(C(C)=O)C(=C(O)C(=O)O1)C2=CC=C(O)C=C2)C3=CC(CC=C(C)C)=C(O)C=C3
Molecular Formula
C24H24O6
Molecular Weight
408.44
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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