BPR3P0128
Product Specifications
CAS Number
1345406-09-8
Target
SARS-CoV
Related Pathways
Microbiology/Virology
Bioactivity
BPR3P0128, a non-nucleoside RNA-dependent RNA polymerase (RdRp) inhibitor, is effective orally and can inhibit various SARS-CoV-2 variants. It exhibits EC 50 values of 0.62 μM for SARS-CoV-2 and 0.14 μM for HCoV-229E, demonstrating potent anti-pancoronavirus activity at submicromolar concentrations. Additionally, BPR3P0128 displays synergistic antiviral effects when used in combination with Remdesivir [1].
Smiles
CC1=C(C2=NC3=C(C(C(O)=O)=C2)C=C(Br)C=C3)C=NN1C4=C(C)C=CC(C)=C4
Molecular Formula
C22H18BrN3O2
Molecular Weight
436.3
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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