BMV109

BMV109 is a quenched probe designed to emit fluorescence upon being cleaved and covalently bound by active cathepsin proteases. This property of BMV109 is utilized in tumor imaging [1] [2].

S(=O)(=O)(C1=C(C=2C3=C([O+]=C4C2C=CC(=C4)N5C=6C(CC5)=CC(S(=O)(=O)O)=CC6)C=C(C=C3)N7C=8C(CC7)=CC(S(=O)(=O)[O-])=CC8)C=CC=C1)N9CCC(C(NCCNC(=O)C%10=C(F)C(F)=C(OCC([C@@H](NC([C@H](CC%11=CC=CC=C%11)NC(OCC%12=CC=CC=C%12)=O)=O)CCCCNC(CCCCCN%13C=%14C(C(C)(C)C%13=CC=CC=CC%15=[N+](CC)C=%16C(C%15(C)C)=CC(S(=O)(=O)[O-])=CC%16)=CC(S(=O)(=O)O)=CC%14)=O)=O)C(F)=C%10F)=O)CC9