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BKN-1

Product Specifications

CAS Number

1607831-82-2

Target

Apoptosis|||Autophagy

Related Pathways

Apoptosis|||Autophagy

Bioactivity

BKN-1, a bifunctional ligand, facilitates the tracking of mtG4s (G-quadruplexes, four-stranded DNA structures containing Hoogsteen bonds) formation via far-red emission and can induce mitochondrial dysfunction. This compound exhibits anti-tumor properties, potentially causing mtDNA loss, damaging mitochondrial integrity, reducing ATP levels, and triggering ROS imbalance, which can lead to apoptosis and autophagy [1].

Smiles

CC1(C)C2=C([N+](C)=C1C=CC=3C=C4C(=CC3)N(CC)C=5C4=CC=CC5)C=CC=6C2=CC=CC6.[I-]

Molecular Formula

C31H29IN2

Molecular Weight

556.48

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Product Datasheet

https://www.targetmol.com/attachment/DataSheet/212215650402172974/T85862

Available Sizes

Curated Selection

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