BKN-1
Product Specifications
CAS Number
1607831-82-2
Target
Apoptosis, Autophagy
Related Pathways
Apoptosis, Autophagy
Bioactivity
BKN-1, a bifunctional ligand, facilitates the tracking of mtG4s (G-quadruplexes, four-stranded DNA structures containing Hoogsteen bonds) formation via far-red emission and can induce mitochondrial dysfunction. This compound exhibits anti-tumor properties, potentially causing mtDNA loss, damaging mitochondrial integrity, reducing ATP levels, and triggering ROS imbalance, which can lead to apoptosis and autophagy [1].
Smiles
CC1(C)C2=C([N+](C)=C1C=CC=3C=C4C(=CC3)N(CC)C=5C4=CC=CC5)C=CC=6C2=CC=CC6.[I-]
Molecular Formula
C31H29IN2
Molecular Weight
556.48
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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