BIO-7488
Product Specifications
CAS Number
2573211-25-1
Target
IRAK
Related Pathways
Immunology/Inflammation|||NF-?B
Bioactivity
BIO-7488, a potent and selective IRAK4 inhibitor, is orally active and penetrates the CNS, exhibiting an IC50 of 0.6 nM for IRAK4 and > 30 ?M for hERG [1].
Smiles
CC12CC(C1)(CO2)C=3N=C4N(C3)C=C(C(NC5=C6N(N=C5)C=C(C)C=N6)=O)C(OC(C)C)=N4
Molecular Formula
C23H25N7O3
Molecular Weight
447.49
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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