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Arylsulfonamide 64B

Product Specifications

CAS Number

1342890-83-8

Target

HIF/HIF Prolyl-Hydroxylase

Related Pathways

Chromatin/Epigenetic, Metabolism

Bioactivity

Arylsulfonamide 64B (HIF inhibitor 64B), an inhibitor of the hypoxia-induced factor (HIF), not only suppresses hypoxia/HIF-induced expression of c-Met and CXCR4 but also decreases primary tumor growth and metastasis in a uveal melanoma mouse model [1].

Smiles

N(S(=O)(=O)C1=CC(OC)=C(OC)C=C1)(CC=2N=C3C(=CC2)OC(C)(C)C=C3)C4CCC4

Molecular Formula

C23H28N2O5S

Molecular Weight

444.54

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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