ART0380
Product Specifications
CAS Number
2267316-76-5
Target
ATM/ATR
Related Pathways
PI3K/Akt/mTOR signaling, DNA Damage/DNA Repair
Purity
>99.99%
Bioactivity
ART0380 is a potent, selective, orally available, ATP-competitive ATR kinase inhibitor (IC50=51.7 nM) with antitumor activity for the study of ataxia telangiectasia mutated (ATM) cancer.
Smiles
C[C@H]1N(CCOC1)C2=NC(C3=CC=NC(N)=C3)=NC(N=S(C4CC4)(C)=O)=C2
Molecular Formula
C18H24N6O2S
Molecular Weight
388.49
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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