ART0380

Product Specifications

CAS Number

2267316-76-5

Target

ATM/ATR

Related Pathways

PI3K/Akt/mTOR signaling|||DNA Damage/DNA Repair

Purity

>99.99%

Bioactivity

ART0380 is a potent, selective, orally available, ATP-competitive ATR kinase inhibitor (IC50=51.7 nM) with antitumor activity for the study of ataxia telangiectasia mutated (ATM) cancer.

Smiles

C[C@H]1N(CCOC1)C2=NC(C3=CC=NC(N)=C3)=NC(N=S(C4CC4)(C)=O)=C2

Molecular Formula

C18H24N6O2S

Molecular Weight

388.49

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

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