AR/AR-V7-IN-1
Product Specifications
CAS Number
2964558-54-9
Target
Androgen Receptor
Related Pathways
Endocrinology/Hormones
Bioactivity
AR/AR-V7-IN-1 (Compound 20i) serves as an inhibitor of AR/ARV7, demonstrating an IC 50 of 172.85 nM. It effectively inhibits cell growth in the LNCaP and 22RV1 cell lines, with IC 50 values of 4.87 μM and 2.07 μM, respectively. Additionally, it shows potent tumor growth inhibition in a 22RV1 xenograft study. AR/AR-V7-IN-1 is useful in studies related to prostate cancer [1].
Smiles
N(C1CN(CCCF)C1)C2=CC=C(CC3CCN(CC3)C4=CC=C(C(N[C@@H]5CC[C@@H](OC6=CC(Cl)=C(C#N)C=C6)CC5)=O)N=N4)C=C2
Molecular Formula
C36H43ClFN7O2
Molecular Weight
660.22
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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