AQIM-I
Product Specifications
CAS Number
2247881-73-6
Target
Survivin
Related Pathways
Apoptosis
Bioactivity
AQIM-I is a survivin inhibitor that reduces survivin expression and colony formation. It promotes reactive oxygen species (ROS) production, apoptosis, cell cycle arrest, DNA damage, and autophagy. Moreover, AQIM-I effectively inhibits nonsmall cell lung cancer cells A549, with an IC 50 value of 9 nM [1].
Smiles
[I-].O=C1C2=CC=3C=CC=CC3C=C2C(=O)C4=C1N(C=[N+]4C)C
Molecular Formula
C17H13IN2O2
Molecular Weight
404.2
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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