Antitumor agent-100
Product Specifications
CAS Number
2841750-32-9
Target
PDE, Apoptosis
Related Pathways
Apoptosis, Metabolism
Bioactivity
Antitumor Agent-100 (compound A6) is a molecular gel and apoptosis inducer targeting PDE3A-SLFN12 with an IC50 of 0.3 μM, demonstrating potent antitumor activity. This orally available agent binds to the PDE3A enzyme pocket, recruiting and stabilizing SLFN12 which disrupts protein translation and induces apoptosis [1].
Smiles
ClC1=C2C(NC=3N(C2)CC(=O)N3)=CC=C1C4=CC=C(C)C=C4
Molecular Formula
C17H14ClN3O
Molecular Weight
311.77
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
A07938-1-Fluoro488 100 µg/Vial
Anti-OTULIN Antibody Picoband® Fluoro488 Conjugated
Sign In for Pricing
View Details 
MBS6412364-01 0.1 mL
CPT1A (Carnitine Palmitoyltransferase 1A, CPT1, CPT1-L, L-CPT1) (FITC)
Sign In for Pricing
View Details MBS6412364-02 5x 0.1 mL
CPT1A (Carnitine Palmitoyltransferase 1A, CPT1, CPT1-L, L-CPT1) (FITC)
Sign In for Pricing
View Details 