Anti-infective agent 9
Product Specifications
CAS Number
758689-17-7
Target
Parasite
Related Pathways
Microbiology/Virology
Bioactivity
Anti-infective agent 9 (compound 1) acts as a Plasmodium falciparum inhibitor, demonstrating an IC 50 of 600 nM. It effectively reduces pyruvate levels and disrupts the TCA cycle within Plasmodium. This compound also exhibits robust metabolic stability and minimal toxicity to human liver cells. Research indicates that the potential targets of Anti-infective agent 9 for inhibiting Plasmodium falciparum do not include 1-deoxy-D-xylulose-5-phosphate synthase (DXPS) [1].
Smiles
FC(F)(F)C1=CC=C(C=C1)NC2=NC(=CS2)C=3SC(=NC3C)N
Molecular Formula
C14H11F3N4S2
Molecular Weight
356.39
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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