Anticancer agent 188
Product Specifications
CAS Number
1207377-56-7
Target
Reactive Oxygen Species, DNA/RNA Synthesis
Related Pathways
DNA Damage/DNA Repair, Cell Cycle/Checkpoint, Metabolism, Immunology/Inflammation, NF-κB
Bioactivity
Compound D43 (Anticancer agent 188) inhibits DNA synthesis in TNBC cells, causing cell cycle arrest at the G2/M phase. It exhibits anticancer properties by inducing ROS-mediated apoptosis and DNA damage [1].
Smiles
O=C1N=C2C(=NC(=NN2C)C3=CC=CC=C3F)C(=O)N1C
Molecular Formula
C13H10FN5O2
Molecular Weight
287.25
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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