ALR-27
Product Specifications
CAS Number
903639-13-4
Target
FLAP
Related Pathways
Immunology/Inflammation
Bioactivity
ALR-27 serves as an antagonist of the 5-lipoxygenase (5-LOX) activating protein FLAP and exhibits anti-inflammatory properties. It effectively inhibits 5-LOX product formation (>80%) in pro-inflammatory M1-MDM without significantly inhibiting 5-LOX directly. Additionally, ALR-27 decreases prostaglandin and leukotriene (LT) production in neutrophils and enhances the production of specialized prolytic mediators in certain human macrophage phenotypes [1].
Smiles
C(CC1=CC=C(O)C=C1)C2CCC(CO2)C3=CC=C(O)C=C3
Molecular Formula
C19H22O3
Molecular Weight
298.38
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
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