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ALR-27

Product Specifications

CAS Number

903639-13-4

Target

FLAP

Related Pathways

Immunology/Inflammation

Bioactivity

ALR-27 serves as an antagonist of the 5-lipoxygenase (5-LOX) activating protein FLAP and exhibits anti-inflammatory properties. It effectively inhibits 5-LOX product formation (>80%) in pro-inflammatory M1-MDM without significantly inhibiting 5-LOX directly. Additionally, ALR-27 decreases prostaglandin and leukotriene (LT) production in neutrophils and enhances the production of specialized prolytic mediators in certain human macrophage phenotypes [1].

Smiles

C(CC1=CC=C(O)C=C1)C2CCC(CO2)C3=CC=C(O)C=C3

Molecular Formula

C19H22O3

Molecular Weight

298.38

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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