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AKR1C3-IN-12

Product Specifications

CAS Number

891075-67-5

Target

Reductase

Related Pathways

Metabolism, Endocrinology/Hormones

Bioactivity

AKR1C3-IN-12 (compound 2j), an inhibitor of aldo-keto reductase 1C3 (AKR1C3), exhibits potent activity with an IC50 of 27 nM. It has been shown to enhance the effectiveness of Gemcitabine and Cisplatin in treating bladder cancer [1].

Smiles

O=C(NC1=CC=C(C=C1)C)C2=CC=3C=CC=C(O)C3OC2=N

Molecular Formula

C17H14N2O3

Molecular Weight

294.3

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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