AKR1C3-IN-12
Product Specifications
CAS Number
891075-67-5
Target
Reductase
Related Pathways
Metabolism, Endocrinology/Hormones
Bioactivity
AKR1C3-IN-12 (compound 2j), an inhibitor of aldo-keto reductase 1C3 (AKR1C3), exhibits potent activity with an IC50 of 27 nM. It has been shown to enhance the effectiveness of Gemcitabine and Cisplatin in treating bladder cancer [1].
Smiles
O=C(NC1=CC=C(C=C1)C)C2=CC=3C=CC=C(O)C3OC2=N
Molecular Formula
C17H14N2O3
Molecular Weight
294.3
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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