Abd110
Product Specifications
CAS Number
3021581-79-0
Target
ATM/ATR|||PROTACs
Related Pathways
PROTAC|||DNA Damage/DNA Repair|||PI3K/Akt/mTOR signaling
Bioactivity
Abd110 (compound 42i), a Lenalidomide-based PROTAC ATR kinase degrader, selectively reduces levels of ATR and phospho-ATR while not impacting the related kinases ATM and DNA-PKcs [1].
Smiles
O=C(NC=1C=CC=CC1)C=2N=C(C=NC2N)C3=CC=C(C=C3)S(=O)(=O)NCCCCCC(=O)NCCCC#CC4=CC=CC=5C(=O)N(CC45)C6C(=O)NC(=O)CC6
Molecular Formula
C41H42N8O7S
Molecular Weight
790.89
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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