MYC degrader 1

2946670-96-6

Molecular Glues|||c-Myc

Cell Cycle/Checkpoint|||PROTAC

A80.2HCl, a MYC degrader, restores pRB1 protein activity and reduces MYC-dependent CDK4/6 resistance, demonstrating antitumor activity [1].

O=C1NC(=O)C(N2C(=O)C3=CC=C(C=C3C2)CNCC4CCN(C=5N=CC(=CC5C(F)(F)F)C6=CC=CC(Cl)=C6)CC4)CC1

C32H31ClF3N5O3

626.07

Cool pack

-20°C

https://www.targetmol.com/attachment/DataSheet/212215416695554075/T85534