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MYC degrader 1

Product Specifications

CAS Number

2946670-96-6

Target

Molecular Glues|||c-Myc

Related Pathways

Cell Cycle/Checkpoint|||PROTAC

Bioactivity

A80.2HCl, a MYC degrader, restores pRB1 protein activity and reduces MYC-dependent CDK4/6 resistance, demonstrating antitumor activity [1].

Smiles

O=C1NC(=O)C(N2C(=O)C3=CC=C(C=C3C2)CNCC4CCN(C=5N=CC(=CC5C(F)(F)F)C6=CC=CC(Cl)=C6)CC4)CC1

Molecular Formula

C32H31ClF3N5O3

Molecular Weight

626.07

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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