4-Br-Bnlm
Product Specifications
CAS Number
1654775-71-9
Target
Others|||HSP
Related Pathways
Others|||Cytoskeletal Signaling|||Metabolism
Bioactivity
4-Br-Bnlm, with an EC 50 of 0.96 µM, acts as a selective inhibitor of glucose-regulated protein 94 (Grp94) . It effectively reduces both mutant and wild-type misfolded myocilin proteins in cells, thereby enhancing the clearance of toxic forms of myocilin and diminishing myocilin toxicity [1] [2].
Smiles
C(OC)(=O)C1=C(CCC=2N(CC3=CC=C(Br)C=C3)C=CN2)C(Cl)=C(O)C=C1O
Molecular Formula
C20H18BrClN2O4
Molecular Weight
465.72
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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ALDH4A1 (Aldehyde Dehydrogenase Family 4 Member A1, Delta-1-pyrroline-5-carboxylate Dehydrogenase, Mitochondrial, P5C Dehydrogenase, ALDH4, P5CDH)
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