(Rac) -SAG
Product Specifications
CAS Number
364590-63-6
Target
Smo
Related Pathways
Stem Cells
Bioactivity
(Rac) -SAG, an isoform of SAG, is a potent Smoothened (Smo) receptor agonist (EC?? = 3 nM; Kd = 59 nM) that activates the Hedgehog signaling pathway and counteracts Cyclopamine's inhibition of Smo [1] [2] [3].
Smiles
N(C(=O)C1=C(Cl)C=2C(S1)=CC=CC2)(CC3=CC(=CC=C3)C=4C=CN=CC4)C5CCC(NC)CC5
Molecular Formula
C28H28ClN3OS
Molecular Weight
490.06
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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