(Z) -SU14813
Product Specifications
CAS Number
452105-23-6
Target
VEGFR, PDGFR, Tyrosinase
Related Pathways
Proteases/Proteasome, Angiogenesis, Tyrosine Kinase/Adaptors
Purity
0.9818
Bioactivity
(Z) -SU14813 is a novel tyrosine kinase inhibitor with anticardiogenic and antitumor activity that inhibits VEGFR-2, PDGFR-β, and FLT3 phosphorylation in xenograft tumors in a dose- and time-dependent manner.
Smiles
C(=C\1/C=2C(NC1=O)=CC=C(F)C2)\C3=C(C)C(C(NC[C@@H](CN4CCOCC4)O)=O)=C(C)N3
Molecular Formula
C23H27FN4O4
Molecular Weight
442.48
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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