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(Z) -SU14813

Product Specifications

CAS Number

452105-23-6

Target

VEGFR, PDGFR, Tyrosinase

Related Pathways

Proteases/Proteasome, Angiogenesis, Tyrosine Kinase/Adaptors

Purity

0.9818

Bioactivity

(Z) -SU14813 is a novel tyrosine kinase inhibitor with anticardiogenic and antitumor activity that inhibits VEGFR-2, PDGFR-β, and FLT3 phosphorylation in xenograft tumors in a dose- and time-dependent manner.

Smiles

C(=C\1/C=2C(NC1=O)=CC=C(F)C2)\C3=C(C)C(C(NC[C@@H](CN4CCOCC4)O)=O)=C(C)N3

Molecular Formula

C23H27FN4O4

Molecular Weight

442.48

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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