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Salvinorin A Carbamate

Product Specifications

CAS Number

858345-57-0

Target

Others, Opioid Receptor

Related Pathways

Endocrinology/Hormones, GPCR/G Protein, Others, Neuroscience

Bioactivity

Salvinorin A carbamate, a potent κ-opioid receptor (KOR) full agonist, exhibits nearly the same potency as salvinorin A, with EC50 values of 6.2 and 4.5 nM, respectively, for activating the human KOR to augment the binding of [35S]GTPγS. Enhancing biological stability, the addition of a carbamate group to salvinorin A reduces deacetylation.

Smiles

COC(=O)[C@@H]1C[C@H](OC(N)=O)C(=O)[C@H]2[C@@]1(C)CC[C@H]1C(=O)O[C@@H](C[C@]21C)c1ccoc1

Molecular Formula

C22H27NO8

Molecular Weight

433.457

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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