SLP7111228 hydrochloride
Product Specifications
CAS Number
1449768-48-2
Target
Others
Related Pathways
Others
Bioactivity
SLP7111228 is a potent, selective SPHK1 inhibitor with Ki values of 0.048 μM for SPHK1 and >10 μM for SPH2K, showing a concentration-dependent reduction of sphingosine-1-phosphate (S1P) in U937 cells without affecting sphingosine levels. In vivo, it dose-dependently lowers S1P blood levels in rats.
Smiles
Cl.CCCCCCCCc1ccc(cc1)-c1noc(C[C@@H]2CCCN2C(N)=N)n1
Molecular Formula
C22H34ClN5O
Molecular Weight
420
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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