N-Deacetylcolchicine
Product Specifications
CAS Number
3476-50-4
Target
Others|||Microtubule Associated
Related Pathways
Others|||Cytoskeletal Signaling
Bioactivity
Trimethylcolchicinic acid methyl ether (HAN 76504), an antimitotic agent, blocks microtubule assembly by attaching to tubulin and inhibiting its polymerization. It enhances tubulin's intrinsic GTPase activity, induces apoptosis across various normal and tumor cell lines, and activates the JNK/SAPK pathway. Currently unnamed, it is referred to by a provisional code name in line with MedKoo Chemical Nomenclature (https://www.medkoo.com/page/naming) for ease of communication.
Smiles
O(C)C1=C2C=3C(=CC(=O)C(OC)=CC3)[C@@H](N)CCC2=CC(OC)=C1OC
Molecular Formula
C20H23NO5
Molecular Weight
357.4
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
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