What is the catalog number for Myrothecine A?

The catalog number for Myrothecine A is T85069.

What sizes are available for Myrothecine A?

Myrothecine A is available in the following size(s): 10 mg, 50 mg.

How many pack sizes does Myrothecine A come in?

Myrothecine A is available in 2 different pack sizes.

Is Myrothecine A in stock?

Myrothecine A is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Myrothecine A?

Myrothecine A is manufactured by Molfinity.

What is the estimated delivery time for Myrothecine A?

Estimated delivery time for Myrothecine A is approximately 10 business day(s), depending on your location.

Myrothecine A

Product Specifications

CAS Number

910292-40-9

Target

JNK, Others, PARP, Caspase, Bcl-2 Family, Apoptosis, Cytochromes P450

Related Pathways

Chromatin/Epigenetic, Apoptosis, Proteases/Proteasome, Metabolism, MAPK, Others, DNA Damage/DNA Repair

Bioactivity

Myrothecine A, a trichothecene mycotoxin discovered in M. roridum, exhibits anticancer properties. It effectively inhibits the proliferation of various cancer cell lines, specifically A549, MCF-7, HepG2, and SMMC-7721, with IC50 values of 95, 70, 60, and 25 μM, respectively. At a concentration of 50 μM, Myrothecine A induces G1 cell cycle arrest in HepG2 cells and promotes apoptosis in SMMC-7721 cells by elevating levels of Bax and cleaved caspase-3, -5, and -8.