TM5441 sodium
Product Specifications
CAS Number
2319722-53-5
Target
Others, Apoptosis, PAI-1
Related Pathways
Apoptosis, Metabolism, Others
Bioactivity
TM5441, an orally bioavailable plasminogen activator inhibitor-1 (PAI-1) inhibitor with IC50 values ranging from 13.9 to 51.1 μM, effectively induces intrinsic apoptosis across multiple human cancer cell lines. Additionally, it mitigates Nω-nitro-l-arginine methyl ester-induced cardiac hypertension and vascular senescence [1] [2].
Smiles
N(C(COCC(NC1=C(C(O)=O)C=C(Cl)C=C1)=O)=O)C=2C=C(C=CC2)C=3C=COC3.[Na]
Molecular Formula
C21H16ClN2NaO6
Molecular Weight
450.8
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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