BIBO3304 diTFA
Product Specifications
CAS Number
2310085-85-7
Target
Others, Neuropeptide Y Receptor
Related Pathways
GPCR/G Protein, Others, Neuroscience
Bioactivity
BIBO3304 (diTFA), a selective neuropeptide Y (NPY) Y1 receptor antagonist, demonstrates oral efficacy. It exhibits high affinity for Y1 receptors in both humans and rats, with IC50 values of 0.38 nM and 0.72 nM, respectively. Additionally, BIBO3304 (diTFA) enhances bone-tendon healing via the Wnt/β-catenin signaling pathway [1] [2] [3].
Smiles
C(C(O)=O)(F)(F)F.C(C(N[C@@H](C(NCC1=CC=C(CNC(N)=O)C=C1)=O)CCCNC(=N)N)=O)(C2=CC=CC=C2)C3=CC=CC=C3
Molecular Formula
C33H37F6N7O7
Molecular Weight
757.68
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
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