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Trans-J-113863

Product Specifications

CAS Number

202796-42-7

Target

Others, CCR

Related Pathways

Others, Immunology/Inflammation, Microbiology/Virology, GPCR/G Protein

Bioactivity

Trans-J-113863 serves as a potent antagonist of chemokine receptors CCR1 and CCR3, effectively inhibiting MIP-1α-induced chemotaxis in CCR1 transfectants and eotaxin-induced chemotaxis in CCR3 transfectants, with respective half-maximal inhibitory concentrations (IC50) of 9.57 nM and 93.8 nM [1] [2].

Smiles

C(N[C@@H]1CC[N@+](CC=2CCCCCCC2)(CC)CC1)(=O)C3C=4C(OC=5C3=CC(Cl)=CC5)=CC=C(Cl)C4.[I-]

Molecular Formula

C30H37Cl2IN2O2

Molecular Weight

655.44

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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