Trans-J-113863
Product Specifications
CAS Number
202796-42-7
Target
Others, CCR
Related Pathways
Others, Immunology/Inflammation, Microbiology/Virology, GPCR/G Protein
Bioactivity
Trans-J-113863 serves as a potent antagonist of chemokine receptors CCR1 and CCR3, effectively inhibiting MIP-1α-induced chemotaxis in CCR1 transfectants and eotaxin-induced chemotaxis in CCR3 transfectants, with respective half-maximal inhibitory concentrations (IC50) of 9.57 nM and 93.8 nM [1] [2].
Smiles
C(N[C@@H]1CC[N@+](CC=2CCCCCCC2)(CC)CC1)(=O)C3C=4C(OC=5C3=CC(Cl)=CC5)=CC=C(Cl)C4.[I-]
Molecular Formula
C30H37Cl2IN2O2
Molecular Weight
655.44
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
GTR15260637 1 Vial
Lentiviral mouse Cr2 shRNA (UAS) - Lentiviral mouse Cr2 shRNA (UAS, GFP) (100)
Sign In for Pricing
View Details TP762223 50 µg
IL23 Receptor (IL23R) (NM_144701) Human Recombinant Protein
Sign In for Pricing
View Details 
BNC680210-100 1x 100 µL
Giardia lamblia (BB1.1E5), CF568 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
C2267-30L-ML490 100 µL
CD16 (Fc gamma RIII alpha, NK cells) (MaxLight 490)
Sign In for Pricing
View Details 
171597-APC 100 µL
Human Immunodeficiency Virus Type 1, p24 (HIV-1 p24) (APC) discontinued
Sign In for Pricing
View Details