DBCO-PEG2-NHS ester
Product Specifications
CAS Number
2585653-12-7
Target
ADC Linker
Related Pathways
Antibody-drug Conjugate/ADC Related
Bioactivity
DBCO-PEG2-NHS ester is a click chemistry reagent featuring an azide group and an NHS ester, designed for copper-free Click Chemistry. It specifically and efficiently reacts with primary amines (e.g., lysine residue side chains or aminosilane-coated surfaces) under neutral or slightly basic conditions to form stable covalent bonds. The inclusion of a hydrophilic PEG spacer enhances water solubility and provides a flexible linkage, reducing steric hindrance during ligation. This compound, intended for research use only [1], is ideal for applications requiring precise and efficient bioconjugation.
Smiles
C(CCC(NCCOCCOCCC(ON1C(=O)CCC1=O)=O)=O)(=O)N2C=3C(C#CC=4C(C2)=CC=CC4)=CC=CC3
Molecular Formula
C30H31N3O8
Molecular Weight
561.58
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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